At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.

Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine, and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visitneurocrine.com, and follow the company on LinkedIn, X (Formerly Twitter) and Facebook. (*in collaboration with AbbVie)

About the Role:

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Your Contributions (include, but are not limited to):

• Independently conductin vitroandin vivometabolite identification studies including (but not limited to) preparing and analyzing samples for LC-MS/MS analysis, processing data and interpretation of data to understand metabolic pathways

• Develop and implement suitable analytical LC separation methods and troubleshooting analytical issues with minimal supervision

• Develop and optimize MS methods to obtain structural characterization of metabolites of interest

• Radioanalysis (14C, 3H, etc.,) and radio-profiling of in vitro and in vivo biological samples for quantitation and identification of metabolites

• Perform routine instrument maintenance, repair and may troubleshoot complex instrument issues

• Writing protocols and reports, compiling, analyzing, and interpreting data

• Ensuring timely delivery of results in line with project schedules

• Prepare data summaries and present results to peers, colleagues, project team and leadership teams

• Possess excellent written and verbal technical communication skills and the demonstrated ability to lead, guide and influence teams in decision making

• PhD in Biochemistry, Drug Metabolism, or closely related discipline with 2+ years of experience in the industrial discovery and development of small and large molecular therapeutics; or MS with 5+ years of experience or BS with 10+ years of experience

• Expertise and working knowledge of biotransformation of small molecules, enzymology and LC-MS/MS methodology

• Experience with handling of biological samples containing radioactivity used in ADME studies

• Experience with isolation of metabolite and NMR a plus

• Ability to balance multiple projects and handle competing responsibilities

• Demonstrate strong communication skills with the ability to integrate diverse perspectives, deliver critical messaging, and influence leaders/key partners

• Collaborative team behaviors and aspiration to build and sustain relationships with R&D customers and the wider scientific community

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Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.

We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.

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